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Composition: Each milliliter contains 2 MIU of colistin (sulfate)
Mechanism of action: Cleistin is an antibiotic from the polymyxin family that has a significant effect on gram-negative bacteria. Although the mechanism of action of this antibiotic has not been determined correctly, but it seems that this antibiotic causes their destruction by affecting the cell membrane of microorganisms, that’s why they consider colistin to be a bactericidal antibiotic, which in the state of growth or rest, kills microbes. and less resistance to this combination has been observed.
Indications: prevention, control and treatment of diseases caused by bacteria sensitive to colistin, such as hemorrhagic gastroenteritis, salmonellosis
Administration and dosage:
Poultry: 250 ml of colicide per 1000 liters of drinking water for 3 consecutive days (equivalent to 75,000 units per kilogram of body weight).
Calves and lambs: 0.25 ml of the solution per 10 kg of body weight 2 times a day for 3 – 4 consecutive days
Drug interactions: It is not recommended in livestock and poultry with kidney disorders.
Withdrawal time: Stop taking the drug two days before slaughter
Drug interactions: The simultaneous administration of colistin with bivalent cations, unsaturated fatty acids and quaternary ammonium compounds causes drug interactions.
Note After opening the bottle, the contents must be consumed within 60 days. The prepared olution containing the medicine must be consumed within 24 hours
Storage: keep in less than 25 ͦ c and protect it away from straight sun light.
